Headache is a common symptom in acupuncture clinics. Acupuncturist often has to deal with it every day. 69% of urban inhabitants in China suffer from headaches. But how can acupuncture help it? This lecture introduces that acupuncture treatment has effect to produce endorphin, relieve muscle tension and improve circulation. According to TCM, headache is differentiated into wind-cold, wind-heat, liver fire, blood stagnation, phlegm, qi and blood deficiency, liver and kidney essence deficiency. There are different treatment acupoints and techniques based on TCM differentiation, as well as 6 clinical headache cases have been discussed in this lecture.